RTG-ReMPro
Publications
2024 and earlier
P1
Proteolytic processing of galectin-3 by meprin metalloproteases is crucial for host-microbiome homeostasis
Bulck, C., Nystrom, E. E. L., Koudelka, T., Mannbar-Frahm, M., Andresen, G., Radhouani, M., Tran, F., Scharfenberg, F., Schrell, F., Armbrust, F., Dahlke, E., Zhao, B., Vervaeke, A., Theilig, F., Rosenstiel, P., Starkl, P., Rosshart, S. P., Fickenscher, H., Tholey, A., Hansson, G. C., and Becker-Pauly, C. (2023)
P2
Abeta34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer's disease progression.
Liebsch, F., Kulic, L., Teunissen, C., Shobo, A., Ulku, I., Engelschalt, V., Hancock, M. A., van der Flier, W. M., Kunach, P., Rosa-Neto, P., Scheltens, P., Poirier, J., Saftig, P., Bateman, R. J., Breitner, J., Hock, C., and Multhaup, G. (2019)
P2
Nanoscale PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.
Adhikari, B., Bozilovic, J., Diebold, M., Schwarz, J. D., Hofstetter, J., Schroder, M., Wanior, M., Narain, A., Vogt, M., Dudvarski Stankovic, N., Baluapuri, A., Schonemann, L., Eing, L., Bhandare, P., Kuster, B., Schlosser, A., Heinzlmeir, S., Sotriffer, C., Knapp, S., and Wolf, E. (2020)
P4
Nanoscale segregation of channel and barrier claudins enables paracellular ion flux.
Gonschior, H., Schmied, C., Van der Veen, R. E., Eichhorst, J., Himmerkus, N., Piontek, J., Gunzel, D., Bleich, M., Furuse, M., Haucke, V., and Lehmann, M. (2022)
VPS34-dependent control of apical membrane function of proximal tubule cells and nutrient recovery by the kidney.
P3
Rinschen MM, Harder JL, Carter-Timofte ME, Zanon Rodriguez L, Mirabelli C, Demir F, Kurmasheva N, Ramakrishnan SK, Kunke M, Tan Y, Billing A, Dahlke E, Larionov AA, Bechtel-Walz W, Aukschun U, Grabbe M, Nielsen R, Christensen EI, Kretzler M, Huber TB, Wobus CE, Olagnier D, Siuzdak G, Grahammer F, Theilig F. (2022)
Sci Signal. 29;15(762):eabo7940. doi: 10.1126/scisignal.abo7940. Epub 2022 Nov 29.
P5
A pharmacological master key mechanism that unlocks the selectivity filter gate in K(+) channels.
Schewe, M., Sun, H., Mert, U., Mackenzie, A., Pike, A. C. W., Schulz, F., Constantin, C., Vowinkel, K. S., Conrad, L. J., Kiper, A. K., Gonzalez, W., Musinszki, M., Tegtmeier, M., Pryde, D. C., Belabed, H., Nazare, M., de Groot, B. L., Decher, N., Fakler, B., Carpenter, E. P., Tucker, S. J., and Baukrowitz, T. (2019)
P6
The human disease gene LYSET is essential for lysosomal enzyme transport and viral infection.
Richards, C. M., Jabs, S., Qiao, W., Varanese, L. D., Schweizer, M., Mosen, P. R., Riley, N. M., Klussendorf, M., Zengel, J. R., Flynn, R. A., Rustagi, A., Widen, J. C., Peters, C. E., Ooi, Y. S., Xie, X., Shi, P. Y., Bartenschlager, R., Puschnik, A. S., Bogyo, M., Bertozzi, C. R., Blish, C. A., Winter, D., Nagamine, C. M., Braulke, T., and Carette, J. E. (2022)
P7
Physiological shedding and C-terminal proteolytic processing of TMEM106B.
Held S, Erck C, Kemppainen S, Bleibaum F, Giridhar NJ, Feederle R, Krenner C, Juopperi SP, Calliari A, Mentrup T, Schröder B, Dickson DW, Rauramaa T, Petrucelli L, Prudencio M, Hiltunen M, Lüningschrör P, Capell A, Damme M. (2024)
Cell Rep. 28;44(1):115107. doi: 10.1016/j.celrep.2024.115107.
P8
Planar cell polarity signalling coordinates heart tube remodelling through tissue-scale polarisation of actomyosin activity.
Merks, A. M., Swinarski, M., Meyer, A. M., Muller, N. V., Ozcan, I., Donat, S., Burger, A., Gilbert, S., Mosimann, C., Abdelilah-Seyfried, S., and Panakova, D. (2018)
P9
An otopetrin family proton channel promotes cellular acid efflux critical for biomineralization in a marine calcifier.
Chang, W. W., Matt, A. S., Schewe, M., Musinszki, M., Grussel, S., Brandenburg, J., Garfield, D., Bleich, M., Baukrowitz, T., and Hu, M. Y. (2021)